CEPT is a cocktail of small molecules developed at the National Institutes of Health (NIH). It contains four components, and CEPT is an acronym for them: Chroman 1, Emricasan, Polyamines, and Trans-ISRIB.
In human ES cells and human iPS cells (human pluripotent stem cells [hPSCs]), CEPT prevents cellular stress and DNA damage during cell passage.1) Like Y-27632, a known potent ROCK inhibitor, it improves the viability of hPSCs during cell passage and cryopreservation.
Compared to existing methods, CEPT also improves cell viability in stem cell research, including embryoid body and organoid formation, single cell cloning, and genome editing using hPSCs.1-5)
Our product is a ready-to-use CEPT cocktail solution that has been tested for sterility and does not require preparation. This filter-sterilized solution can be added directly to the culture medium. It will aid in regenerative medicine research.