Extracellular vesicles (EVs), including exosomes, contain various nucleic acids and proteins. Messenger RNA (mRNA) and microRNA (miRNA) in particular are attracting attention as functional molecules in intercellular communication mediated by exosomes. In EV research, the extraction and purification of RNA is a crucial step that impacts downstream analysis, such as real-time PCR, microarrays, and next-generation sequencing, making the selection of an appropriate kit essential. Fujifilm Wako offers the "microRNA Extractor® Kit for Purified EV," optimized for the extraction and purification of RNA from purified EVs.