Extracellular vesicles (EV), including exosomes, contain microRNAs (miRNA) derived from secretory cells, and their role has attracted attention. In general, miRNA in EV are comprehensively analyzed by next-generation sequencing and microarray. The process of extracting RNA from EV is an important step that is directly linked to the analysis results. Fujifilm Wako has developed the RNA Extractor™ Kit for Purified EV, an RNA extraction kit optimized for purified EV.