When analyzing a target compound in a biological sample containing a large amount of protein such as serum by HPLC, deproteinization that requires time and labor is required. Wakopak® Wakosil® GP-N6 is a HPLC column that allows direct injection of protein-containing samples.
In HPLC analysis by Wakopak® Wakosil® GP-N6, macromolecules, such as proteins, pass through the column due to the hydrophilic structure of the modifier, while relatively small molecules, such as drugs, are retained by reverse-phase distribution, etc.