Mouse leukemia inhibitory factor (LIF) was initially identified as a cytokine capable of inducing macrophage differentiation in M1 murine myeloid leukemic cells. This cytokine was later shown to have a differentiation-inhibiting activity on embryonic stem (ES) cells. Currently, it is used for culturing mouse ES cells to maintain their pluripotency.
This product is a recombinant mouse LIF expressed in E. coli.
It contains a 6xHis-tag at the C-terminus. The StemSure series consist of a group of products that are guaranteed to support both the proliferation and pluripotency of mouse ES cells. To achieve these high-quality standards, we use the mouse ES cell line D3 and routinely perform cell growth, colony formation assays and alkaline phosphatase (ALP) staining.