| Grade : | for Immunochemistry |
| Storage Condition : | Keep at -20 degrees C. |
| Host : | Mouse |
| Clone No. : | MO389 |
| Classification : | Monoclonal |
| Catalogue/Product Number | Package Size | COA Download |
|---|---|---|
|
018-27283
|
50uL |
Glial fibrillary acidic protein (GFAP) is an intermediate filament protein with a molecular weight of approximately 50 kDa. GFAP is widely recognized as a marker for astrocytes, as it is primarily expressed in these cells within the central nervous system. It is thought to play a role in the structural organization of astrocytes. Previous studies have also shown that it is essential for the proliferation of reactive astrocytes and the formation of glial scars1-2). GFAP expression is known to increase under such pathological conditions compared to the normal state.
Anti GFAP, Monoclonal Antibody(MO389) is a mouse monoclonal antibody against GFAP. It is suitable for astrocyte staining in both immunohistochemistry and immunocytochemistry.
| Clonality | Monoclonal |
|---|---|
| Antigen | Synthetic peptide (CQIRETpSLDTKS) |
| Host | Mouse |
| Formulation | PBS, 50% Glycerol |
| Conjugate | Unconjugated |
| Cross-reactivity | Human, Mouse |
| Application | Immunocytochemistry 1:1,000 Immunohistochemistry 1:500 Western Blotting 1:10,000 |
| Outline | This product is for research use only. Do not administer it to human. Glial fibrillary acidic protein (GFAP) is an intermediate filament with a molecular weight of approximately 50 KDa and is known to localize in astrocytes. Therefore, antibodies recognizing GFAP are used as markers for astrocytes. This product is a monoclonal antibody that specifically recognizes GFAP. [Subclass] IgG1 [Species cross reactivity] human [Experimental adaptation] WB, ICC |
|---|
| Antigen | GFAP |
|---|---|
| Antigen Alias | GFAP Glial Fibrillary Acidic Protein GFAP Cocktail FLJ45472 GFAP - glial fibrillary acidic protein Glial Fibrillary Acidic Protein (GFAP) |
| Subclass | IgG1 |
| Labeling | Unlabeled |